26 Most Powerful Weapons in Fallout 4

Most Powerful Weapons In Fallout 4

This article discusses some of the most powerful weapons in Fallout 4. Fallout 4’s wasteland is a harsh and dangerous place.

The Sole Survivor will encounter difficulties as they set out on their quest to learn what happened to their son Shaun if they are unprepared.

Having the best equipment and weapons is essential for surviving in the Commonwealth, so having the right tools of destruction is crucial.

However, Fallout 4 doesn’t just hand out its best weapons on a silver platter in true open-world survival game fashion.

Many are in obscure or unmarked areas, making it necessary to have the right abilities or even a little luck to find them if you’re looking for a brand-new, potent weapon.

Here are some of the most potent weapons in Fallout 4. 


One of the game’s most distinctive and effective weapons is the cryolator, which, as its name suggests, freezes anything it comes into contact with.

Although the player is shown this weapon within the first ten minutes of gameplay in Vault 111, inside a locked glass case, it doesn’t become available until much later in the game once you’ve leveled your lockpicking skills to Master.

Sadly, the Cryolator’s drawback, as with many uncommon weapons, is a lack of ammunition. To ensure you won’t run out of Cryo rounds and to extend your range, you’ll need to add a crystallizing barrel mod.

However, the crystals’ plodding projectile speed makes it more of a show-off weapon than an effective one.

Kellogg’s Pistol

Although it crosses your path reasonably early in the main plot, this Pistol has a strong punch and is still important throughout the game.

Kellogg’s Pistol fills the traditional video game void of the magnum revolver with tremendous stopping power and respectable range and accuracy. It becomes even more lethal in VATS because a critical hit allows you to reload your AP. 

Furthermore, the problem is that it needs—44 highly uncommon rounds. Although the ammo scavenging perk is helpful in this regard, you should generally reserve this gun for tough battles or devastating sneak attacks. 

Righteous Authority

This is one of the older, more potent weapons that people frequently find, similar to Kellogg’s Pistol.

Thankfully, unlike Kellogg’s, it depends on the much more prevalent fusion cell, which is found everywhere once you start fighting synths. Particularly potent in VATS, critical hits deal double damage and are ready more frequently.

This stacks beautifully with the Better Criticals and Critical Banker perks to deliver hot, laser-like justice if you have good luck.

Furthermore, you’ll detect a distress radio beacon from the Cambridge Police Department as you move south toward Diamond City.

If you follow, you can find a stranded Brotherhood of Steel platoon fighting off a horde of feral ghouls. Talk to PaladinDanse, the group’s leader, after assisting them. This is one of the most powerful weapons in Fallout 4.


Some of the most powerful weapons in the game are melee weapons. The Shishkebab is one of the best melee weapon options and is best described as a flaming sword.

The sword inflicts physical and energetic harm. You will eventually be given the side quest Out of the Fire, which directs you to aid the Finch Farm if you have joined the Minutement.

Moreover, after stealing his father’s priceless sword, Jake Finch joins the local raider gang known as the Forged, and Abraham Finch asks the Sole Survivor to deal with them.

Abraham will permit you to keep the shishkebab if you clean up the nearby Saugus Ironworks factory and defeat the leader Slag to save Jake.

The Problem Solver

In Nuka-World, a simple speech check with the gang leader Mason can earn you access to a simple-to-miss weapon.

Approach Mason in the Bradberton Amphitheater in Nuka Town after becoming the Overseer and receiving orders to speak with the three leaders of the three raider groups from Nuka-World.

Make sure to choose all assertive and aggressive options when speaking with Mason. Some of the checks will require a high Charisma rating for you to pass.

At the conclusion, Mason will be moved by your assertiveness and give you The Problem Solver, one of Fallout 4’s best handmade rifles that increases damage with each additional shot. This is one of the most powerful weapons in Fallout 4.

Furious Power Fist

The Furious Power Fist is a cute little glove that strengthens your fists and increases the amount of damage you deal to the same target when you strike it repeatedly. This one is the best melee weapon in Fallout 4 for anyone who enjoys close-quarters combat.

Furthermore, Swan, a super mutant mercenary, doesn’t want to give it up, so you have to take it off of him. Go to Boston’s city center, close to the Freedom Trail’s starting point and the subway entrance to Vault 114, where Nick Valentine needs to be rescued.

Also, the swan spends the day inactive, with only a small portion of his back protruding from his pond. However, he patrols the pond area between the hours of one and five in the morning.

Grognak’s Axe

Even if you’re not going for a strength-based brawler, it’s a good idea always to carry a dependable melee weapon because the ammunition you rely on can occasionally be in short supply.

This axe also deals significant damage, and the disorientation it causes is particularly helpful if you need to use it to fight your way out of a difficult situation.

Furthermore, on the first floor of Hubris comics, the axe is kept in a locked case (advanced) behind the counter. When you first enter, it seems empty, but it soon fills with ferocious ghouls.

We advise just showing up prepared and possibly throwing a few Molotov cocktails into the back of the store as soon as they peek in. This very special weapon is ideal for a melee build.

Le Fussil Terribles

Most shotguns in the game have short magazines, poor range, slow firing, and slow loading speeds. Le Fusil Terribles is the lone exception, and it’s unquestionably one of the game’s best weapons.

With a unique ability that piles on more damage and makes it especially useful for blasting off limbs, it loads 32 shells at once. It exhibits impressive damage, especially for its range.

Furthermore, it is situated in Libertalia, a raider settlement on the water northeast of the airport. You can find it on top of a crate in the captain’s quarters if you fight your way up a series of boats connected by bridges. This is one of the most powerful weapons in Fallout 4.


This suppressed Pistol is one of the best ways to use 10-millimeter ammunition, which is widely available. It’s great in VATS because of its improved accuracy and more effective use of AP, primarily if you orient your perks in that direction.

Having a suppressor is also a nice perk if you enjoy being covert. Follow the Freedom Trail to the Railroad and connect there to get it.

Deacon will give you Deliverer as payment for completing the Tradecraft quest, which involves breaking into an abandoned Railroad hideout.

Alien Blaster

There are more than just lasers and flaming swords in the post-apocalyptic future. For the more daring survivor, alien blasters are another option.

The catch to this special blaster is that it has very little ammo unless the Science! Perk is fully unlocked, so you’ll want to ensure you do that. In essence, it will allow you to use fusion cells as ammunition.

After assisting the Hubologists in their search, a blaster variant can be discovered in Nuka-World. Also, if you don’t have the DLC, there’s one hidden close to Beantown Brewery and Oberland Station.

To obtain the blaster and some ammunition, enter the nearby cave and defeat the alien with good damage, accuracy, and range. This is one of the most powerful weapons in Fallout 4.

Lorenzo’s Artifact

It should be no surprise that one of Fallout 4’s best weapons, Radiation, serves its primary purpose, given that radiation is one of the wasteland’s greatest threats.

The Sole Survivor can use Lorenzo’s Artifact gun to weaponize the power of gamma rays against their adversaries.

Also, it’s important to remember that even though the weapon is marketed as a radiation weapon, it causes pure damage instead of radiation damage. However, the ability to knock back and stun opponents is beneficial.

Furthermore, you must work for the Cabot family to begin the quest. To receive this gun’s reward, go to the Third Rail in Goodneighbor to meet Edward Deegan. Finish all the Cabot family quests, and support Jack Cabot in his battle against Lorenzo.

Overseer’s Guardian

The Overseer’s Guardian is what you want if you enjoy shooting rifles. In reality, every fired shot fires two bullets rather than one.

To deal severe damage, you can modify this short-barreled combat rifle, which is otherwise normal and fully adjustable.

This gun can kill almost anything in the Commonwealth in a single shot if you invest in the Gun Nut and Rifleman perks.

Moreover, you can purchase the Overseer’s Guardian from Alexis Combes for about 3,000 caps in vault 81, which is south of the Beantown Brewery and east of the city.

One of the few functional societies left in the vaults, 81 still is dedicated to medical research. Give them three fusion cores or be a smooth talker to gain their trust and entry.

Big Boy

It is like a typical Fat Man personal nuclear warhead launcher; only it can simultaneously launch two nuclear weapons.

Also, the best part is that it only uses one priceless warhead. More literal value for your money is excellent because warheads are scarce and expensive.

If super mutant suicide bombers are charging at you, aim for their heads rather than their bombs, as this will help you collect more.

This is readily available from Arturo Rodriguez in the Diamond City market but is ridiculously pricey. If you want to save money, start early and consider purchasing some benefits that will make bartering easier. This is one of the most powerful weapons in Fallout 4.

The Harvester

Owners of the Far Harbor DLC will want to get their hands on this entertaining and distinctive melee weapon, which, in addition to dealing damage and moving very quickly, also stuns enemies. When used against enemies, it emits a terrifying sound as well.

Visit Echo Lake Lumber to locate this. Go to the second floor of the largest building as you secure the site for a potential new settlement. The Harvester will be concealed inside a red trunk waiting for you.

Kremvh’s Tooth

Kremvh’s Tooth, another excellent melee weapon, is located in one of the most mysterious places in the entire Commonwealth.

Also, Kremvh’s Tooth has a special modification that identifies it as a sacrifice blade and increases its damage by adding poison and bleeding. Despite being designated as a machete, it also has a unique shape.

Go to Dunwich Borers, the location of a sinister cult that has established itself there. At the very bottom of the area, inside a tiny tunnel with an unsettling-looking altar, is where you’ll find the machete.


Even though miniguns are generally a lousy choice for weapons, if your character builds calls for one, at least choose the Ashmaker.

This unique variation ignites your targets for a few extra damage points. After the Big Dig quest, if you choose to support Fahrenheit, she will reward you with the best minigun in Fallout 4 as a thank you.

Furthermore, to begin the quest, go to the Goodneighbor and look for Bobbi No-Nose behind a door in one of the winding streets.

Without much explanation, she will make you an offer of employment, and if you accept, she will accompany you on a heist to Diamond City’s strongroom.

However, as is frequently the case, nothing exactly goes as expected. This is one of the most powerful weapons in Fallout 4.

Alien Blaster Pistol

A rare, compact, and potent energy weapon with extraterrestrial origins has appeared in every Fallout game. It deals a ton of damage but relies on a particular round that, beyond the 400 or so it comes with, is probably uncommon.

You can modify the Alien Blaster to work with fusion cells with a slight hit to damage if your Science perk is maxed, but until then, you should only use it when necessary.

There are conflicting rumors regarding the precise cause of the alien saucer crash necessary for you to obtain the gun. Also, many claims that you must finish Vault 75 and/or be level 20 or higher.

Party Starter

The Assaultron merchant in Goodneighbor, KL-E-O, sells a missile launcher called the Party Starter. Additionally, it deals additional damage to enemies with human features.

Ammo for missile launchers typically weighs a lot and requires reloading between shots, which is a disadvantage.

These caveats, however, can also be corrected reasonably quickly with the appropriate mods. Also, it packs a powerful punch and is a fantastic niche weapon for those amusing, niche character builds.

Wastelander’s Friend

From a comical visual perspective, The Wastelander’s Friend is also surprisingly helpful. It is a typical ten-millimeter pistol with an exceptionally long extended magazine.

Increasing the weapon’s ammunition capacity from 8 to 24 can fire three times as many rounds before reloading. Other modifications like a grip and a recon scope are also included.

Also, go to Bunker Hill and look for a vendor named Deb if this sounds right up your alley. This is one of the most powerful weapons in Fallout 4.

The Last Minute

One of Fallout 4’s top energy weapons, The Last Minute is a unique Gauss rifle that deals an extra 50% damage to your adversaries’ limbs. A few well-placed shots to the Deathclaws’ legs will truly save the day if a pack of them is pursuing you.

Furthermore, You must complete the Minutemen-only quest Old Guns at the Castle before it becomes accessible. Also, you can speak with Ronnie Shaw, who will sell you the gun once the Castle is safe.


The Splattercannon is another strong weapon for players with the Nuka-World DLC. Given that the Splattercannon has the same Legendary effect as The Problem Solver, it’s an excellent backup for those who missed the opportunity to finish the dialogue check with Mason and obtain The Problem Solver.

Furthermore, the same target takes more damage from each subsequent shot. Also, it’s one of the best handmade rifles in the game and a solid choice.

Moreover, with enough money, it’s easy to buy it from Aaron Corbett over at the Nuka-Town marketplace. Just be prepared to pay a fortune for it unless you have the excellent Charisma to negotiate a lower price. This is one of the most powerful weapons in Fallout 4.

Eddie’s Peace

Nick Valentine will give you the job of retrieving the Eddie Winters tapes from various police stations throughout the Commonwealth after you become friends with him.

During the quest A Long Time Coming, this enables you to find the infamous gangster boss and bring him to his hideout in Andrew Station.

Furthermore, you can take Eddie’s special gun, Eddie’s Peace, after you locate and eliminate him. Although it has a few exciting mods, the real treat is the bonus of 25% additional limb damage.

Atom’s Judgement

The most potent melee weapon in the game is this formidable super sled. This otherwise typical sledge has a cracked fusion core in place of the head, which causes 100 more radiation damage.

Atom’s Judgement can deal enormous damage if you spend points on the nuclear physicist intelligence perk.

Furthermore, you must advance through the expansion plot until you encounter the Children of Atom sect, who reside in a former submarine base, to obtain Atom’s Judgement.

The Heretic is a quest that Grand Zealot Richter will assign you to complete to find a former member of their cult who is causing trouble for them on the island.

Also, once you locate Gwyneth, however you decide to handle the situation, go back to Richter, and he will give you Atom’s Judgment as payment.

Nuka Nuke Launcher

The Nuka-Nuke Launcher, the most recent iteration of the destructive Fat Man mini-nuke catapult, uses an improved variety of the basic Mini-nukes called, you guessed it, Nuka-nukes.

The modified ammunition makes the Nuka-nuke launcher one of the most potent weapons in the game, dealing significantly more damage than the mini-nukes.

However, you must complete the “Cappy in a Haystack” quest to obtain this weapon. After that, Sierra will give you a code to enter John-Caleb Bradberton’s office.

2076 World Series Baseball Bat

Some things, like deathclaws and super mutants, can be sent flying through the air by this baseball bat because of its extreme power.

This baseball bat, which ranks highly among the best melee weapons in Fallout 4, is the only weapon of choice for those unique melee character builds.

Furthermore, after navigating the facility’s tight security, you’ll find the magical home run bat in Jamaica Plain’s town hall basement. You could later sell it to a collector, but it’s worth too much. This is one of the most powerful weapons in Fallout 4.

Final Judgement

If a minigun that can fire every round produced in under a minute isn’t enough for you, a Gatling laser might be what you need. A fusion core typically used to charge a powered armor suit is required for Final Judgment.

Arthur Maxson, the leader of the Brotherhood of Steel, prefers using it and won’t relinquish it easily. Due to its extensive versatility, it is also one of the best weapons in Fallout 4.

The quest Airship Down, in which the Sole Survivor battles the Brotherhood on behalf of the Institute, can naturally lead to the acquisition of the weapon.

As an alternative, Railroad members can hold off until the quests Rockets’ Red Glare, in which Maxson challenges the Sole Survivor after they’ve detonated explosives inside the Prydwen, or Precipice of War, in which they can go directly to the Prydwen.

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